The Gemara tells us that one should make sure not to do business before davening and that one should daven before setting out on a trip, and if you do so, Hashem will take care of you.
Rav Shteinman (K’Ayal Ta’arog) explained that if one is going to another city or neighboring Moshav to daven there, it is muttar as the Gemara is only talking about someone who is traveling for business purposes.
The Pela Yoetz (#59 – Derech) tells us that if someone will be traveling after Chatzos one should even daven Mincha at home before he goes. He goes on to say that if one would do this, you are guaranteed a safe and secure journey.
And Rabba bar Ḥinnana Sava said in the name of Rav: Anyone who can ask for mercy on behalf of another, and does not ask is called a sinner, as it is stated following Samuel’s rebuke of the people: “As for me, far be it from me that I should transgress against the Lord in ceasing to pray for you, but I will teach you the good and the right way” (I Samuel 12:23). Had Samuel refrained from prayer, he would have committed a sin.
Berachos 12b – Sefaria
The Gemara tells us that anybody who is able to pray on behalf of another should do so. One can ask – why doesn’t the Gemara simply say that one should pray on behalf of others, and if one is unable to, its ok. Why the seemingly extra words of “Anyone who can ask”?
Rav Steinman Zt’l explained so beautifully, that when it comes to interpersonal relationships, many times one has in his or her heart a grudge or feeling of jealousy against another. A prayer for someone that you bear a grudge against, is not considered a wholehearted prayer and is not necessarily answered.
Therefore, he explains, the Gemara says that only one who is able to pray wholeheartedly and drop any grudges against the other, should pray for his friend.